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Administration to Wistar rats for two several years of 2 g/kg bw every day sodium saccharin in the drinking-drinking water or of four g/kg bw every day in the diet regime diminished the weight get markedly; fluid ingestion was elevated from the latter team and diminished in the previous. The normal urinary pH of males in the first team had risen to

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However, later on reports confirmed that the enhanced incidence of bladder cancer was only applicable to rats, due to their distinct biology. The results of the sooner experiments weren't transferable to human beings. In 2000, saccharin was taken off the government’s listing of recognised carcinogens, plus the warning labels were being discontinu

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